Speakers > Jorg TOST

Laboratoire Epigénétique et environnement, Institut de biologie François Jacob, Centre National de Recherche en Génomique Humaine, Evry

Presentation

Jörg Tost received his PhD in genetics from the University of Saarbrücken (Germany) in 2004 devising novel methods for the analysis of haplotypes and DNA methylation patterns. After a postdoctoral stay in the technology development department of the Centre National de Génotypage (CNG, Evry, France), he led the Epigenetics groups from 2006-2012, before becoming Director of Laboratory for Epigenetics and Environment at the Centre National de Génotypage (part of the CEA-Institut de Génomique).

Research summary

The laboratory is involved in the development and application of technologies to analyse DNA methylation, miRNAs and other epigenetic modifications quantitatively at high resolution at target loci and genome-wide using state-of-the-art sequencing technologies as well as the development of bioinformatic tools for the processing of such data. While initially focussing on the analysis of DNA methylation patterns implicated in tumourigenesis, the laboratory has extended the analysis to immune-related and neurodegenerative diseases and in particular how environmental exposure influences epigenetic profiles.